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Clinical and Scientific Studies

 

Healthy nutritionists wouldn't be recommending Garcinia Cambogia extract without factual or scientific basis. What caught their attention was the study conducted by a reputable and well-respected health and wellness specialist Dr. Julie Chen whose research studies on the extract and those taking it showed a causal relationship between Garcinia Cambogia consumption and an average loss of 10 lbs in weight every month. The supplement containing the Gambooge extract was taken without altering the eating habits or workout routines. More encouraging was the observation that in all cases of Gambooge extract consumption, weight loss occurred even when doing nothing to correct unhealthy diets or getting sufficient exercise, and without any adverse side effects common with dieting changes. The study showed that participants lost 17 lbs in three months. This result came from reducing 10.5% of body weight and 16 % of overall body fat.


Effects of hydroxycitric acid (HCA) natural extract when taken alone or combined with Gymnema sylvestre (GSE) and niacin-bound chromium (NBC) extracts on weight management. (Diabetes Obesity Metabolism. 2004 May;6(3):171-80) An 8-week double-blind randomized and placebo-controlled study involving 60 mildly obese participants aged 21-50 with Body Mass Index (BMI) of 26 kg/m2 was conducted in Elluru, India. Participants were randomly grouped in three, with Group A getting HCA, Group B getting a combination of HCA, NBC and GSE, and Group C getting a placebo instead. The study monitored changes in BMI, body weight, lipid profiles, appetite, leptin serum in the blood and excretion of fat metabolites in the urine and feces.


Results: After 8 weeks, both groups A and B showed decreased BMI and body weight by 5-6%. Aggregated food intake, cholesterol (low-density lipoproteins and triglycerides), and blood serum leptin levels were reduced significantly in both groups A and B while a non-significant effect was documented in the third control group.


Conclusion: HCA extract taken alone or in tandem with GSE and NBA reduces appetite, inhibits fat metabolism and decreases overall body weight without affecting the central nervous system.


Effects of hydroxycitric acid on appetite (Physiology Behaviour. 2000 Oct 1-15;71(1-2):87-94) This double-blind, placebo-controlled parallel group study was participated in by 89 mildly obese females administered with 5020-kJ diets for 12 weeks. Forty-two participants in group A was prescribed with 400-mg caplets of Garcinia Cambogia an hour before each meal for a n aggregated daily dosage of 2.4 g. Forty-seven participants in Group B ingested placebos in the same quantity and timing. Body weight was measured once every o0ther week for 12 weeks and compared with baseline weight measurements.

Result: Both groups showed diminished body weights with Group A achieving a significantly higher weight loss (3. 7 kg versus 2.4 kg).


Conclusion: While not overly prominent, HCA from Garcinia Cambogia confirmed earlier studies on the efficacy of HCA in reducing weight. There is strong causal link between Hydroxycitric Acid and inhibiting Citrate Lyase enzyme action that results in diminished metabolism of fatty acids. HCA has also been shown to mimic antidepressant action with its ability to increase serotonine levels thereby suppressing appetite by fooling the brain into letting you feel full after consuming food at a level that would not otherwise give a feeling of fullness. There is sufficient evidence that shows Hydroxycitric Acid extracts to effectively suppress appetites and achieve weight loss.

Simple consumption on a regular basis results in weight loss minus the side effects associated with dieting regimens gives the extract an advantage over other diet supplements that work as fat blockers and appetite suppressants. This gives The Garcinia Cambogia the qualities that have now endeared its efficacy to those who have tried the extract, creating its reputations as the "Holy Grail" in weight management.

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